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Bioengineering

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Protein Kinase C-delta hæmmer peptid formulering bruger guld nanopartikler

Article DOI: 10.3791/58741-v • 06:06 min • March 9th, 2019
March 9th, 2019 •
1, 2, 1, 1, 1, 1, 1,3
1Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, 2Respiratory Medicine Research Laboratory, Institute of Translation Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 3Institute of Medical Science, Faculty of Medicine, University of Toronto

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Vi har tidligere brugt en guld nanopartikel peptid hybrid intravenøst levere en syntetisk peptid, protein kinase C-delta hæmmer, hvilket reducerede iskæmi-reperfusion-induceret akut lunge skade. Her viser vi de detaljerede protokollen af narkotika formuleringen. Andre intracellulære peptider kan være formuleret på samme måde.

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Bioteknologi sag 145 biomaterialer intravenøs medicinafgivelse peptid therapeutics drug levering køretøj aminosyre drug formulering
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