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Murine Cervical Aortic Transplantation Modell mit einer modifizierten Non-Suture Manschettentechnik
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Murine Cervical Aortic Transplantation Modell mit einer modifizierten Non-Suture Manschettentechnik

Article DOI: 10.3791/59983-v • 10:11 min • November 2nd, 2019
November 2nd, 2019 •
1, 1, 1, 1, 2, 1, 1, 1, 1, 1, 1, 1, 1, 1,3
1Department of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, 2Walter-Brendel-Centre of Experimental Medicine, Ludwig Maximilian University of Munich, 3Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, University of Cologne

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Hier stellen wir ein Protokoll der heterotopischen Aortentransplantation bei Mäusen mit der Nicht-Naht-Manschettentechnik in einem zervikalen Murin-Modell vor. Dieses Modell kann verwendet werden, um die zugrunde liegende Pathologie der chronischen Allograft-Vaskulopathie (CAV) zu untersuchen und kann helfen, neue therapeutische Wirkstoffe zu bewerten, um ihre Bildung zu verhindern.

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Medizin Ausgabe 153 Aortentransplantation chronische Allograft Vaskulopathie Nicht-Naht-Manschettentechnik vaskuläre glatte Muskelzelle Mikrochirurgie.
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