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Immunology and Infection

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JoVE Journal Immunology and Infection
Serotip 1 Streptococcus pneumoniae suşunda Mutantların İnşası 519/43
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Journal (Immunology and Infection)
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An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Journal (Immunology and Infection)
An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
 
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Serotip 1 Streptococcus pneumoniae suşunda Mutantların İnşası 519/43

Article DOI: 10.3791/61594-v • 06:06 min • September 11th, 2020
September 11th, 2020 •
1, 2, 3, 2, 1
1Faculty of Infections and Tropical Diseases, Department of Infection Biology, London School of Hygiene and Tropical Medicine, 2Division of Medicine, University College London, 3Division of Infection and Immunity, University College London UCL

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Burada, doğal olarak DNA ve intihar plazmidini elde etme kabiliyeti kullanılarak genetik olarak değiştirilebilen bir S. pneumoniae serotip 1 suşu 519/43'ü tanımlıyoruz. İlke kanıtı olarak, pnömolysin (kat) geninde izojenik bir mutant yapıldı.

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İmmünoloji ve Enfeksiyon Sayı 163 Serotip 1 S. pneumoniae Mutagenez doğal yeterlilik Menenjit kuşağı
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