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Neuroscience

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JoVE Journal Neuroscience
Robust og meget reproducerbar generation af kortikale hjerneorganoider til modellering af hjernens neuronale ældning in vitro
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Robust og meget reproducerbar generation af kortikale hjerneorganoider til modellering af hjernens neuronale ældning in vitro

Article DOI: 10.3791/63714-v • 05:40 min • May 5th, 2022
May 5th, 2022 •
*1, *1, 1
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland
* These authors contributed equally

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I denne undersøgelse giver vi en detaljeret teknik til et simpelt, men robust kortikalt organoidkultursystem ved hjælp af standard feederfrie hPSC-kulturer. Dette er en hurtig, effektiv og reproducerbar protokol til generering af organoider, der modellerer aspekter af hjerneældning in vitro.

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Neurovidenskab udgave 183
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