Naoto Hirano Department of Immunology University of Toronto Biography Publications Institution JoVE Articles Naoto Hirano has not added a biography. If you are Naoto Hirano and would like to personalize this page please email our Author Liaison for assistance. Publications BET Bromodomain Inhibition Enhances T Cell Persistence and Function in Adoptive Immunotherapy Models The Journal of Clinical Investigation. Sep, 2016 | Pubmed ID: 27548527 Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors PloS One. 2016 | Pubmed ID: 27213277 CD4(+) and CD8(+) TCRβ Repertoires Possess Different Potentials to Generate Extraordinarily High-avidity T Cells Scientific Reports. Mar, 2016 | Pubmed ID: 27030642 CDR3β Sequence Motifs Regulate Autoreactivity of Human Invariant NKT Cell Receptors Journal of Autoimmunity. Apr, 2016 | Pubmed ID: 26748722 Adoptive T Cell Therapy Targeting CD1 and MR1 Frontiers in Immunology. 2015 | Pubmed ID: 26052329 Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy Cancer Immunology Research. Sep, 2015 | Pubmed ID: 25943533 Specific Roles of Each TCR Hemichain in Generating Functional Chain-centric TCR Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25710913 Human Cell-based Artificial Antigen-presenting Cells for Cancer Immunotherapy Immunological Reviews. Jan, 2014 | Pubmed ID: 24329798 Ex Vivo 拡張自己の Cd4 陽性 T 細胞を用いたひと CD8 T 細胞の助け。 PloS One. 2012 | Pubmed ID: 22279573 IL 21 STAT 3 依存的にひと Cd8 T 細胞における準最適 Lck 独立 MAPK の活性を補うことができます。 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2012 | Pubmed ID: 22238455 [The Cutting Edge of Antitumor Adoptive Cell Therapy] [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. Oct, 2011 | Pubmed ID: 21971251 人工の抗原提示細胞を用いた HLA DP4 制限アンチ サバイビン Th1 と Th2 応答の誘導。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2011 | Pubmed ID: 21705450 The Third Consensus Conference on the Treatment of Aplastic Anemia International Journal of Hematology. Jun, 2011 | Pubmed ID: 21617886 In Vitro 教育 Cd8 陽性 T 細胞を用いたヒトにおける抗腫瘍性メモリを設立。 Science Translational Medicine. Apr, 2011 | Pubmed ID: 21525398 人間の細胞に基づく人工 APC のパネルは、流行の HLA 対立遺伝子によって制限長寿命の抗原特異的 Cd4 陽性 T 細胞の拡大できます。 International Immunology. Nov, 2010 | Pubmed ID: 21059769 Juvenile Myelomonocytic Leukemia: Epidemiology, Etiopathogenesis, Diagnosis, and Management Considerations Paediatric Drugs. 2010 | Pubmed ID: 20034338 その反対の免疫学的効果の解離はインターロイキン 21 による抗腫瘍 Cd 8 + T 細胞反応の最適化にとって重要です。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2008 | Pubmed ID: 18829491 Clinical Impact of HLA-DR15, a Minor Population of Paroxysmal Nocturnal Haemoglobinuria-type Cells, and an Aplastic Anaemia-associated Autoantibody in Children with Acquired Aplastic Anaemia British Journal of Haematology. Jul, 2008 | Pubmed ID: 18537977 長命抗 Cd8 陽性リンパ球養子療法、人工の抗原提示細胞を使用して生成します。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007 | Pubmed ID: 17363542 Volcanism in Response to Plate Flexure Science (New York, N.Y.). Sep, 2006 | Pubmed ID: 16873612 免疫原性 Cd8 T 細胞エピトープの同定は、推定される腫瘍関連抗原若年性骨髄単球性白血病に対するガンマ グロビンから派生。 Blood. Oct, 2006 | Pubmed ID: 16778141 効率的なプレゼンテーションの当然のことながら加工 HLA クラス I 人工抗原提示細胞によるペプチドの効果的な抗腫瘍応答生成のため。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2006 | Pubmed ID: 16707591 CD83リガンドの関与は、抗原特異性のためにCD8 + T細胞と選択的濃縮の長期拡大を誘導する Blood. Feb, 2006 | Pubmed ID: 16239433 The Chemical Structure of the Hawaiian Mantle Plume Nature. Aug, 2005 | Pubmed ID: 16100780 日本の再生不良性貧血患者における抗kinectinとアンチPMS1抗体の存在 British Journal of Haematology. Jan, 2005 | Pubmed ID: 15638857 よくある再生不良性貧血患者で検出された自己抗体 Blood. Dec, 2003 | Pubmed ID: 12947009 共有腫瘍関連抗原はP450 1B1の特異的細胞傷害性T細胞により認識されたシトクロム Blood. Nov, 2003 | Pubmed ID: 12869499 臨床応用の可能性:人間のプライマリおよびメモリー細胞傷害性Tリンパ球応答を効率的に抗原提示細胞としてCD40活性化B細胞の手段によって誘導される Blood. May, 2002 | Pubmed ID: 11964299 生成 Tingxi Guo1,2, Toshiki Ochi*2, Munehide Nakatsugawa*2, Yuki Kagoya2, Mark Anczurowski1,2, Chung-Hsi Wang1,2, Muhammed A. Rahman2, Kayoko Saso2, Marcus O. Butler1,2, Naoto Hirano1,2 1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network JoVE 54697 면역학 및 감염병학
生成 Tingxi Guo1,2, Toshiki Ochi*2, Munehide Nakatsugawa*2, Yuki Kagoya2, Mark Anczurowski1,2, Chung-Hsi Wang1,2, Muhammed A. Rahman2, Kayoko Saso2, Marcus O. Butler1,2, Naoto Hirano1,2 1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network JoVE 54697 면역학 및 감염병학