Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research (Video) | JoVE

Stephanie J. Hachey; Daniela Gaebler; Christopher C. W. Hughes

doi:10.3791/65865

Preparing a Microfluidics-Based Vascularized Human Micro-Tumor Model

September 15th, 2023

Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research (Video) | JoVE

01:43 min

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Preparing a Vascularized Micro-Tumor System Using Human Cells for Studying Tumors and Drug Responses (Video) | JoVE

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Introducing Human Cells into a Microfluidic Device to Investigate Tumor Progression in a Vascularized Micro-Tumor System (Video) | JoVE

03:51 min

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Stephanie J. Hachey¹, Daniela Gaebler¹, Christopher C. W. Hughes^1,2

¹Molecular Biology and Biochemistry, University of California, Irvine, ²Biomedical Engineering, University of California, Irvine

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This protocol presents a physiologically relevant tumor-on-a-chip model to perform high-throughput basic and translational human cancer research, advancing drug screening, disease modeling, and personalized medicine approaches with a description of loading, maintenance, and evaluation procedures.

Article

Preparing a Microfluidics-Based Vascularized Human Micro-Tumor Model

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