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Journal / Genetics / 小鼠卵母细胞在减数分裂过程中对人类基因功能的评估…
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Genetics

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JoVE Journal Genetics
小鼠卵母细胞在减数分裂过程中对人类基因功能的评估
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小鼠卵母细胞在减数分裂过程中对人类基因功能的评估

Article DOI: 10.3791/57442-v • 11:13 min • April 10th, 2018
April 10th, 2018 •
*1,2, *3, 1,2, 3
1IVI-RMA New Jersey, 2Jefferson College of Biomedical Sciences, Thomas Jefferson University, 3Department of Genetics, Rutgers, The State University of New Jersey
* These authors contributed equally

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随着与人类疾病相关的遗传变异开始显露出来, 开发系统以迅速评估那些被确定的变种的生物学意义变得越来越重要。本协议描述了在女性减数分裂过程中使用小鼠卵母细胞评估人类基因功能的方法。

Tags

遗传学 问题 134 减数分裂 卵母细胞 体检 基因变异 染色体分离 生育率
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