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Journal / Genetics / 探索序列空间,识别调节RNA结合蛋白的结合位点…
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探索序列空间,识别调节RNA结合蛋白的结合位点
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探索序列空间,识别调节RNA结合蛋白的结合位点

Article DOI: 10.3791/59635-v • 11:34 min • August 9th, 2019
August 9th, 2019 •
1
1Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder

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序列特异性对基因调控至关重要。识别特定序列的调控蛋白对基因调控非常重要。为这种蛋白质定义功能结合位点是一个具有挑战性的生物学问题。此处描述了一种用于识别RNA结合蛋白结合位点的迭代方法,适用于所有RNA结合蛋白。

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遗传学 问题 150 RNA 结合蛋白 迭代选择扩增 拼接 聚丙胺-片位/3'拼接位点 SELEX 试管中的序列进化
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