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Protocole de dosimétrie du corps entier pour la thérapie par radionucléide Peptide-Receptor (PRRT)
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Protocole de dosimétrie du corps entier pour la thérapie par radionucléide Peptide-Receptor (PRRT) : Image planaire 2D et méthodes hybrides d’image 2D-3D SPECT/CT

Article DOI: 10.3791/60477-v • 09:49 min • April 24th, 2020
April 24th, 2020 •
1, 1, 2, 3, 3, 3, 3, 3, 3, 3, 3, 3, 4, 5, 3, 1
1Medical Physics Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 2Oncology Pharmacy, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 3Nuclear Medicine Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 4Radiation Research Unit, Istituto Europeo di Oncologia (IEO) IRCCS, Milano, Italy, 5Medical Physics Unit, Istituto Europeo di Oncologia (IEO) IRCCS, Milano, Italy

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Cette méthode estime la dose absorbée de différentes structures pour le peptide-récepteur-radionucléide-thérapie (PRRT) avec la possibilité d’éviter le chevauchement d’organe sur les projections 2D. Les images planaires en série du corps entier permettent d’estimer les doses moyennes absorbées le long du corps tout entier, tandis que l’approche hybride, combinant des images planaires et l’image 3D-SPECT/CT, surmonte les limites du chevauchement de la structure.

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Médecine Numéro 158 dosimétrie imagerie planaire du corps entier dosimétrie hybride théragnostique PSMA protecteurs SPECT
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