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Immunology and Infection

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JoVE Journal Immunology and Infection
Therapeutische Bewertung der fäkalen Mikrobiota-Transplantation in einem Interleukin-10-defizienten Mausmodell
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Journal (Immunology and Infection)
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Therapeutische Bewertung der fäkalen Mikrobiota-Transplantation in einem Interleukin-10-defizienten Mausmodell

Article DOI: 10.3791/63350-v • 05:41 min • April 6th, 2022
April 6th, 2022 •
1,2, 1, 2, 1
1Division of Gastroenterology, Department of Internal Medicine, University of Texas Medical Branch at Galveston, 2Department of Gastroenterology, Xiangya Hospital of Central South University

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Das Zusammenspiel von genetischer Anfälligkeit, Schleimhautimmunität und mikroökologischem Darmmilieu ist an der Pathogenese entzündlicher Darmerkrankungen (IBD) beteiligt. In dieser Studie wandten wir die fäkale Mikrobiota-Transplantation bei IL-10-defizienten Mäusen an und untersuchten ihre Auswirkungen auf Dickdarmentzündungen und Herzfunktion.

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Immunologie und Infektion Ausgabe 182 entzündliche Darmerkrankungen fäkale Mikrobiota-Transplantation Colitis ulcerosa Morbus Crohn Dysbiose Interleukin 10
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