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Establishment and Confirmation of a Postnatal Right Ventricular Volume Overload Mouse Model (Video) | JoVE

Modified Arteriovenous Fistula Surgery to Establish the RV Volume Overload Mouse Model

Article DOI: 10.3791/65372-v • 01:37 min • June 9th, 2023
June 9th, 2023 •
*1, *2, 3, 4, 2,5,6
1Department of Pediatric Intensive Care Unit, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiaotong University, 2Department of Thoracic and Cardiovascular Surgery, Shanghai Children’s Hospital, School of Medicine, Shanghai Jiaotong University, 3Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, 4Department of Radiology, Huangpu Branch, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 5Institute of Pediatric Translational Medicine, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiaotong University, 6Shanghai Institute for Pediatric Congenital Heart Disease, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiaotong University
* These authors contributed equally

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Postnatal høyre ventrikkel volumoverbelastning musemodell medfødt hjertesykdom utviklingsstadier myokard abdominalarteriovenøs fistel morfologiske forandringer hemodynamiske forandringer ultralyd av abdomen ekkokardiografi histokjemisk farging overlevelse suksessrate for fistel RV-forstørrelse fortykket frivegg økning i slagvolum økning i systolisk trykk i bov lungeklaffregurgitasjon remodellering av lungearterier arteriovenøs fistelkirurgi modellstatus Bekreftelse
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