Deep Well Plate
Deep Well Plate - Related Videos
10:57
Generation of Greater Bacterial Biofilm Biomass using PCR-Plate Deep Well Microplate Devices
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Cited by 2 •
2022
This protocol presents methodology to perform biofilm growth and biomass measurements using self-assembled deep well PCR-plate devices for high-throughput 96-well pegged lid static biofilm screening.
11:09
Deep Brain Stimulation with Simultaneous fMRI in Rodents
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Cited by 21 •
2014
This protocol describes a standard method for simultaneous functional magnetic resonance imaging and deep brain stimulation in the rodent. The combined use of these experimental tools allows for the exploration of global downstream activity in response to electrical stimulation at virtually any brain target.
13:29
Jet Impinging on an Inclined Plate
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2023
Source: Ricardo Mejia-Alvarez and Hussam Hikmat Jabbar, Department of Mechanical Engineering, Michigan State University, East Lansing, MI The goal of this experiment is to demonstrate how a fluid flow exerts forces on structures by conversion of dynamic pressure into static pressure. To this end, we will make a plane jet impinge on a flat plate and will measure the resulting pressure distribution along the plate. The resultant force will be estimated by integrating the product between the...
09:45
In vivo Imaging of Deep Cortical Layers using a Microprism
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Cited by 11 •
2009
Right-angle microprisms inserted into the mouse neocortex allows for deep imaging of multiple cortical layers with a viewpoint typically found in slice. One-millimeter microprisms offer a wide field-of-view (~900 μm) and spatial resolutions sufficient to resolve dendritic spines. We demonstrate layer V neuronal imaging and neocortical vascular imaging using microprisms.
10:53
Serial Dilutions and Plating: Microbial Enumeration
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2023
Source: Jonathan F. Blaize1, Elizabeth Suter1, and Christopher P. Corbo1 1 Department of Biological Sciences, Wagner College, 1 Campus Road, Staten Island NY, 10301 Quantitative assessment of prokaryotes can be onerous given their abundance, propensity for exponential proliferation, species diversity within a population, and specific physiological needs. Compounding this challenge, is the four-phase nature in which bacteria replicate (lag, log, stationary and death). The ability to accurately...
FAQs
The deeper wells increase the amount of material that each position can hold compared with standard microplates. This added capacity supports mixing, incubation, centrifugation, and compound storage without requiring immediate transfer to another container. As a result, researchers can handle larger biological samples in parallel while simplifying sample processing and maintaining a consistent plate-based workflow.
Each well functions as an independent vessel, allowing different samples, reagents, or experimental conditions to be handled simultaneously within one plate. This arrangement organizes many reactions or cultures in a consistent format and supports parallel processing. It is especially useful when experiments require repeated operations across numerous samples, such as reagent mixing, incubation, or screening.
The main practical distinction is well capacity. Deep wells accommodate larger sample volumes than standard microplates, so they are better suited to workflows requiring substantial material or multiple processing steps in the same vessel. Standard microplates may be sufficient for lower-volume operations, whereas the deeper format supports sample handling, storage, and processing at greater capacity.
A typical workflow places samples or reagents into individual wells, performs operations such as mixing, incubation, centrifugation, or storage, and then transfers or analyzes the processed material as needed. Multichannel pipettes and automated systems can handle corresponding positions across the plate, helping standardize repeated steps and reduce manual transfers during high-throughput processing.
They are useful when many biological samples must undergo similar processing while retaining enough volume for the experiment. Applications described for this format include nucleic acid purification, protein studies, microbial growth, and screening assays. The plate format combines higher sample capacity with parallel handling, making it suitable for workflows that would otherwise require numerous individual vessels.
Using one plate for multiple processing stages can increase sample capacity while reducing transfer steps and manual labor. Compatibility with multichannel pipettes and automated systems also promotes consistent handling across wells. Fewer transfers may lower contamination risk, while the organized format helps laboratories process nucleic acids, proteins, microbial samples, or screening experiments more efficiently.