Lateral Skull Base Surgery
Lateral Skull Base Surgery - Related Videos
09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Cited by 3 •
2021
We present a protocol to integrate diffusion MRI tractography in patient work-up to endoscopic endonasal surgery for a skull base tumor. The methods for adopting these neuroimaging studies in the pre- and intra-operative phases are described.
08:28
Rodent Stereotaxic Surgery
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2023
Stereotaxic (or stereotactic) surgery is a method used to manipulate the brain of living animals. This technique allows researchers to accurately target deep structures within the brain through the use of a stereotaxic atlas, which provides the 3D coordinates of each area with respect to anatomical landmarks on the skull. After the skull is exposed, anesthetized animals are mounted on a specialized instrument known as a stereotaxic frame, which enables the precise placement of experimental...
08:30
A Method to Make a Craniotomy on the Ventral Skull of Neonate Rodents
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Cited by 6 •
2014
A surgical method is described to expose the ventral skull in neonate rats. Using this approach it is possible to open a craniotomy to perform acute electrophysiology and two-photon microscopy experiments in the brainstem of anesthetized pups.
00:08
Survivable Stereotaxic Surgery in Rodents
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Cited by 50 •
2008
The monitoring of extracellular neurotransmitter levels in distinct brain regions of freely moving animals offers insights on the link between neurotransmitter release and behavior. In vivo microdialysis coupled with electrochemical detection provides excellent anatomical and chemical resolution; and information on how basal neurotransmission is altered by pharmacological or physiological manipulations.
09:44
Imaging Glioma Initiation In Vivo Through a Polished and Reinforced Thin-skull Cranial Window
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Cited by 12 •
2012
By combining a polished and reinforced thin-skull (PoRTS) cranial window and glioblastoma (GBM) cell injection, we can observe glioma initiation and growth from injected GBM cells in the brain of a live mouse longitudinally.
FAQs
Corridor selection depends on the lesion’s location relative to the temporal bone, cerebellopontine angle, cranial nerves, blood vessels, and brain tissue. Surgeons plan an approach that provides sufficient access for disease control while limiting disruption of surrounding structures. This anatomical strategy helps determine whether the procedure should emphasize resection, control, reconstruction, or preservation of specific functions.
Microscopic and endoscopic visualization allow surgeons to inspect confined skull base spaces with greater precision during the operation. These views support careful navigation around cranial nerves, major vessels, and brain tissue, which may be closely associated with the lesion. Their use helps the team pursue the intended treatment while monitoring the anatomical structures relevant to hearing, facial movement, and balance.
Treatment planning weighs the need to remove or control disease against the potential effects on hearing, facial movement, balance, major vessels, and brain tissue. The chosen strategy may therefore prioritize complete resection, controlled treatment, reconstruction, or observation depending on the lesion and its anatomy. Functional outcomes are considered alongside disease management rather than after the surgical plan is established.
Imaging helps define the lesion’s position and its relationship to the dense anatomy of the temporal bone, cerebellopontine angle, cranial nerves, and blood vessels. This information guides selection of a safe access route and clarifies which functional structures require particular protection. Imaging findings also contribute to decisions among resection, reconstruction, disease control, and observation.
Planning integrates imaging with the expertise of neurosurgical and otologic teams. Together, specialists assess the lesion, identify the most suitable corridor, and consider expected effects on hearing, facial movement, balance, vessels, and brain tissue. This coordinated process supports a treatment plan tailored to the anatomical problem, whether the goal is removal, control, reconstruction, or observation.
The approach may be considered for vestibular schwannomas, meningiomas, cholesteatomas, and selected vascular or congenital lesions. Evaluation does not focus only on whether a lesion can be removed. It also considers disease control, reconstruction needs, and preservation of hearing, facial movement, and balance, allowing treatment decisions to reflect both the lesion and the patient’s functional priorities.