Vitreous Core Aspiration

Vitreous core aspiration is an ophthalmic microsurgical technique that removes the central portion of the eye’s vitreous gel while limiting disturbance to the surrounding vitreous and retina. During vitrectomy, a vitreous cutter applies controlled suction and cutting to aspirate liquefied or gelled vitreous through a small ocular instrument, with infusion maintaining the eye’s volume and pressure. The approach provides access to the retina, reduces traction caused by abnormal vitreous attachments, and can help obtain intraocular samples for diagnostic analysis. It is used in managing conditions such as vitreous hemorrhage, retinal detachment, infection, and other disorders requiring posterior-segment surgery.

Vitreous Core Aspiration - Related Videos

Research

JoVE Journal - Medicine
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Dissection of Human Vitreous Body Elements for Proteomic Analysis

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Cited by 28 •

2011

This video shows an effective technique for differentiating and dissecting the various semi-transparent structures of the human vitreous body in post mortem eyes.

Research

JoVE Journal - Medicine

Whole Vitreous Humor Dissection for Vitreodynamic Analysis

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2015

The goal of this protocol is to show an effective technique to isolate whole, intact vitreous core and cortex from post mortem enucleated porcine eyes.

Research

JoVE Journal - Biology
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Evisceration of Mouse Vitreous and Retina for Proteomic Analyses

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Cited by 39 •

2011

The dissection technique illustrates evisceration of the vitreous, retina, and lens from the mouse eye, separation by centrifugation, and characterization with protein assays.

Education

JoVE Core - Molecular Biology

The Nucleosome Core Particle

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2020

Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins. The paradox Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...

Research

JoVE Journal - Biology
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Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies

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Cited by 6 •

2009

Practicing of fine needle aspiration biopsies (FNAB) by trainees is relatively challenging, due to the lack of an easily available, appropriate lesion. Preparation of an AV phantom lesion for practicing the FNAB procedure and mastering proficiency is relatively easy.

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