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In Vivo Mikroenjeksiyon ve Elektroporasyon Kullanan Somatik Genom Mühendisliği Fare Modelleri
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In Vivo Mikroenjeksiyon ve Elektroporasyon Kullanan Somatik Genom Mühendisliği Fare Modelleri

Article DOI: 10.3791/65131-v • 08:06 min • May 5th, 2023
May 5th, 2023 •
1,2, 1,3, 1,2,3
1Rosalind and Morris Goodman Cancer Research Institute, McGill University, 2Department of Human Genetics, McGill University, 3McGill Integrated Core for Animal Modeling (MICAM), McGill University

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Bu protokol, fare yumurtalık kanalında bölgesel olarak kısıtlanmış CRISPR aracılı genom düzenlemesi için mikroenjeksiyon ve in vivo elektroporasyonu tanımlar.

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Kanser Araştırmaları Sayı 195 CRISPR / Cas genom düzenleme fallop tüpü yumurtalık yumurtalık kanseri in vivo kanser modelleme
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