Quartz Resonator
Quartz Resonator - Related Videos
07:37
Preparation of Macroporous Epitaxial Quartz Films on Silicon by Chemical Solution Deposition
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Cited by 7 •
2015
A protocol is presented for the preparation of piezoelectric macroporous epitaxial films of quartz on silicon by solution chemistry using dip-coating and thermal treatments in air.
02:58
Rodent Brain Microinjection Using a Quartz Microneedle
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2025
Source: Paolone, G., et al. Personalized Needles for Microinjections in the Rodent Brain. J. Vis. Exp. (2018).This video demonstrates a rodent brain microneedle injection using a quartz microneedle with holes. The microneedle is attached to a syringe and micropump to control the delivery rate. The needle with the injection solution is inserted into the brain with the delivery speed set at low. Once positioned, the delivery speed is increased. The needle is withdrawn after a brief pause.
02:52
Resonance
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2020
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds. If nitrite ions do indeed contain a single and a double bond, the two bond lengths are expected to be different. A double bond between two atoms is shorter (and stronger) than a single bond between the same two atoms. However, experiments show that both N–O bonds in NO2− have the same strength and length, and are identical in all other...
08:01
Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
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Cited by 11 •
2016
A new electron paramagnetic resonance (EPR) method, rapid scan EPR (RS-EPR), is demonstrated for 2D spectral spatial imaging which is superior to the traditional continuous wave (CW) technique and opens new venues for in vivo imaging. Results are demonstrated at 250 MHz, but the technique is applicable at any frequency.
07:11
Dissipative Microgravimetry to Study the Binding Dynamics of the Phospholipid Binding Protein Annexin A2 to Solid-supported Lipid Bilayers Using a Quartz Resonator
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Cited by 5 •
2018
Here, we present an experimental protocol that can be employed to determine the binding affinities and mode of interaction of label-free phospholipid-binding protein annexin A2 with immobilized solid-supported bilayers (SLB) by simultaneously measuring the mass uptake and the viscoelastic properties of the protein annexin A2.
FAQs
Surface-bound material can shift the resonant frequency, whereas changes in energy dissipation indicate that the interaction also affects how vibrational energy is lost. Considering both readouts helps distinguish a simple increase in attached mass from changes in the mechanical character of the surface-associated layer. This is particularly useful when studying biological interfaces rather than measuring attachment alone.
The crystal’s characteristic resonance supplies a stable reference for detecting changes at its surface. When material becomes associated with that surface, the measured frequency can move from the reference value. Monitoring this shift turns a microscopic surface event into a time-dependent measurement, allowing researchers to follow biological interactions as they occur rather than relying only on a final measurement.
Energy dissipation reports how surface-associated material affects vibrational losses, not merely how much material is present. A change in this parameter can therefore indicate altered viscoelastic properties, meaning changes in the material’s mechanical response. This readout helps characterize biological layers and interfaces whose behavior cannot be described adequately by mass-related frequency shifts alone.
Quartz-resonator measurements can follow surface binding or cell attachment directly through resonance behavior, without introducing a label into the system. Because the response is collected in real time, the technique can show when a surface process occurs and how its signal develops. This makes it useful for observing dynamic biomolecular interactions and biosensor interfaces.
A basic measurement begins by applying an alternating electrical field to drive the crystal, then monitoring its resonant response as material interacts with the surface. Researchers follow changes in frequency and, where relevant, energy dissipation over time. Comparing these signals with the ongoing surface event supports real-time analysis of binding, attachment, or interface changes.
Within biological techniques, the method is suited to molecular binding, cell attachment, and other biomolecular interactions occurring at a monitored surface. These events change the resonator response, so measurements can track surface processes without relying only on an endpoint observation. The resulting time-resolved information supports analysis of how biological material interacts with biosensor interfaces.
Quartz resonators can characterize thin films and biosensor interfaces by tracking how surface-associated material changes resonance behavior and energy dissipation. Frequency shifts provide information about added material, while dissipation changes help reveal altered viscoelastic properties. Together, these measurements connect an observed electrical response with physical changes in biological or biomolecular layers at the sensing surface.