Peristaltic Pump Flow

Peristaltic pump flow is the movement of fluid through a flexible tube by sequential compression and release, a mechanism that matters in both engineered systems and living organisms. Rotating rollers or coordinated muscle contractions create a traveling region of pressure that propels fluid while limiting direct contact with the pumping mechanism. In biology, this principle drives contents through the gastrointestinal tract, where rhythmic smooth-muscle contractions transport and mix food. Laboratory and medical devices apply the same process for controlled delivery of cell cultures, nutrients, blood, or other sensitive fluids, helping maintain sterility and regulate flow without exposing the fluid to valves or mechanical components.

Peristaltic Pump Flow - Related Videos

Research

JoVE EoE - Assay Techniques

Controlled Infusion of Radiopharmaceutical Agent Using a Peristaltic Pump

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2025

Source: Léa Rubira1, Hélène Sturer1, Louise Combette1, Sandra Santini1, Stéphane Renaud1, Cyril Fersing1,21Nuclear medicine department, Institut régional du Cancer de Montpellier (ICM), Univ Montpellier, 2IBMM, Univ Montpellier, CNRS, ENSCMThis video demonstrates the safe, controlled infusion of a radiopharmaceutical using a peristaltic pump with a dual-line cassette system. The setup includes connecting saline and infusion lines, positioning the shielded vial, and initiating simultaneous...

Education

JoVE Core - Cell Biology

ATP Driven Pumps III: V-type Pumps

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2023

V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient. The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...

ATP Driven Pumps II: P-type Pumps

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2023

The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V. A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...

Research

JoVE Journal - Engineering
Free Sample

A Cost-effective and Reliable Method to Predict Mechanical Stress in Single-use and Standard Pumps

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Cited by 4 •

2015

Shear stress investigations on an oil-water emulsion system result in drop breakup over the experimental time. To count drop sizes in pumping processes, the suitability of inline endoscopy was successfully demonstrated in this protocol.

Pumped Concrete

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2024

Concrete in large quantities can be pumped across long distances for placing in inaccessible sites. This system comprises a hopper that receives concrete from a mixer, a pump to propel the concrete, and pipelines that facilitate its delivery. For direct-acting pumps, the concrete enters the pump via the inlet valve under the action of gravity and suction created by the movement of the piston. This concrete is then forced into the pipeline and out through the outlet valve by the forward movement...

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