Semicircular Canals

Semicircular canals are three fluid-filled structures in the inner ear that detect rotational head movements and help maintain balance, spatial orientation, and stable vision. Arranged roughly at right angles, they contain endolymph and sensory regions called cristae ampullares; when the head rotates, endolymph lags behind because of inertia, bending hair cells and changing their electrical signals. The brain integrates these signals with information from the eyes and other balance organs to coordinate the vestibulo-ocular reflex and posture. Studying the semicircular canals helps explain normal vestibular function and disorders such as vertigo, dizziness, and impaired coordination.

Semicircular Canals - Related Videos

Research

JoVE Journal - Medicine
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Testing of all Six Semicircular Canals with Video Head Impulse Test Systems

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Cited by 26 •

2019

This protocol describes how to correctly perform the video head impulse test with two separate test systems commonly used worldwide. Both the 2D and 3D video head impulse test methods are described.

Research

JoVE Journal - Medicine

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse

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Cited by 37 •

2018

In this study, we describe the posterior semicircular canal approach as a reliable method for inner ear gene delivery in neonatal mice. We show that gene delivery through the posterior semicircular canal is able to perfuse the entire inner ear.

Capturing Flow-weighted Water and Suspended Particulates from Agricultural Canals During Drainage Events

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Cited by 2 •

2017

Nutrients present in particulate form can contribute significantly to the overall loads in agricultural drainage waters. This study describes a novel method to capture flow-weighted water and suspended particulates from farm canal drainage over the entire duration of the drainage event.

The C. elegans Excretory Canal as a Model for Intracellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis in a Single Cell: labeling by GFP-fusions, RNAi Interaction Screen and Imaging

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Cited by 6 •

2017

The C. elegans excretory canal is a unique single-cell model for the visual in vivo analysis of de novo polarized membrane biogenesis. This protocol describes a combination of standard genetic/RNAi and imaging approaches, adaptable for the identification and characterization of molecules directing unicellular tubulogenesis, and apical membrane and lumen biogenesis.

Canalostomy for Local Drug Delivery into the Inner Ear of an Adult Mouse

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2025

This video showcases canalostomy, a procedure that allows local drug delivery into the inner ear of a mouse through the semicircular canal with minimal damage to hearing and vestibular function. This method enables the inoculation of viral vectors, pharmaceuticals, and small molecules into the mouse's inner ear.

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