31 Gauge Insulin Needle

A 31 gauge insulin needle is a fine, hollow medical needle designed to deliver insulin through the skin while limiting discomfort and tissue disruption. Its narrow inner channel guides a measured volume of liquid from a syringe or pen into subcutaneous tissue, and the high gauge number indicates a smaller diameter than lower-gauge needles. In developmental biology, similar fine needles can support the careful administration of hormones, tracers, or experimental compounds in animal models, where minimizing local injury helps preserve normal growth and tissue responses. Understanding needle dimensions and delivery conditions is therefore important for reliable dosing, reproducible experiments, and ethical handling of developing organisms.

31 Gauge Insulin Needle - Related Videos

Research

JoVE Journal - Biology

Insulin Injection and Hemolymph Extraction to Measure Insulin Sensitivity in Adult Drosophila melanogaster

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Cited by 16 •

2011

Conserved insulin signaling pathways found in the fruit fly Drosophila melanogaster make this organism a potential tool for modeling metabolic disorders including type II diabetes. To this end, it is critical to establish physiological assays to effectively measure systemic insulin action in peripheral glucose disposal in the adult fly.

Education

JoVE Core - Physics

Pressure Gauges

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2023

Most pressure gauges, like those on scuba tanks, are calibrated to read zero at atmospheric pressure. Readings from such gauges are called the gauge pressure, which is the pressure relative to atmospheric pressure. When the pressure inside the tank exceeds atmospheric pressure, the gauge reports a positive value. Some gauges are designed to measure negative pressure. For example, many physics experiments must take place in a vacuum chamber, a rigid chamber from which some of the air is pumped...

Research

JoVE Journal - Biology
Free Sample

A Quantitative Assay for Insulin-expressing Colony-forming Progenitors

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Cited by 11 •

2011

A three-dimensional clonogenic assay that allows pancreatic-like progenitors to differentiate into insulin-expressing colonies is described. This method takes advantage of semi-solid media containing methylcellulose, Matrigel and growth factors, in which single progenitors proliferate and differentiate in vitro, permitting quantification of the number of functional progenitors in a population.

Research

JoVE Journal - Medicine
Free Sample

Improving IV Insulin Administration in a Community Hospital

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Cited by 7 •

2012

When compared to the previous paper protocol, implementation of a computerized glucose management system results in a substantial increase in blood glucose concentration measurements within the target range. Using a computerized glucose management system to monitor blood glucose levels, decreases in severe hypoglycemia (<40 mg/dL), clinical hypoglycemia (<70 mg/dL), and hyperglycemia (>180 mg/dL) also can be observed.

Research

JoVE Journal - Medicine
Free Sample

Assessment of Cardiac Function and Energetics in Isolated Mouse Hearts Using 31P NMR Spectroscopy

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Cited by 36 •

2010

Langendorff-mode isolated heart perfusion, in conjunction with 31P NMR spectroscopy, combines the fields of biochemistry and physiology into one experiment. The protocol allows for the dynamic measurement of high energy phosphate content and turnover in the heart while concurrently monitoring physiologic function. When performed correctly, this is a valuable technique in the assessment of cardiac energetics.

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