Lung Structure Visualization

Lung structure visualization is the process of producing images or representations of the lungs to examine their anatomy, organization, and physical changes. It can use modalities such as computed tomography, magnetic resonance imaging, ultrasound, or endoscopic methods, each generating contrast through different interactions with tissues or direct optical access. These approaches reveal airways, alveoli, blood vessels, pleura, and lesions, supporting diagnosis, treatment planning, and monitoring of respiratory disease. In medicine, three-dimensional reconstruction and image-guided assessment also help clinicians relate structure to function while enabling researchers to evaluate development, disease progression, and responses to therapy.

Lung Structure Visualization - Related Videos

Research

JoVE Journal - Immunology and Infection

Precision-cut Mouse Lung Slices to Visualize Live Pulmonary Dendritic Cells

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Cited by 52 •

2017

We describe a method for generating Precision-cut Lung Slices (PCLS) and immunostaining them to visualize the localization of various immune cell types in the lung. Our protocol can be extended to visualize the location and function of many different cell types under a variety of conditions.

Research

JoVE Journal - Medicine
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The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques

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Cited by 18 •

2014

This article describes bronchoscopic techniques in the bovine lung under experimental conditions, i.e. bronchoscopically guided inoculation, bronchoalveolar lavage, bronchial brushing, and transbronchial lung biopsy.

A Simple Method of Mouse Lung Intubation

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Cited by 50 •

2013

This paper describes a striaghforward and efficient method of intubating mice for pulmonary function measurements or pulmonary instillation, that allows the mice to recover and be studied at later times. The procedure involves an inexpensive fiberoptic light source that directly illuminates the trachea.

Research

JoVE Journal - Medicine
Free Sample

Improved Visualization of Lung Metastases at Single Cell Resolution in Mice by Combined In-situ Perfusion of Lung Tissue and X-Gal Staining of lacZ-Tagged Tumor Cells

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Cited by 12 •

2012

The novel protocol reported in the present study allows selective detection of lung metastases at single cell resolution in mice by combined in-situ lung perfusion and fixation and X-Gal staining of lacZ-tagged tumor cells.

The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues

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Cited by 5 •

2018

An animal model is needed to decipher the role of circulating tumor cells (CTCs) in promoting lung colonization during cancer metastasis. Here, we established and successfully performed an in vivo assay to specifically test the requirement of polymeric fibronectin (polyFN) assembly on CTCs for lung colonization.

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