Pre-treatment Scale

The Pre-treatment Scale is a clinical assessment framework used to document a patient’s baseline condition before therapy begins, providing a reference for treatment planning and later comparison. It typically applies standardized criteria, symptom ratings, or functional measures at the initial evaluation, converting observations into scores that characterize disease severity or clinical status. In medicine, this baseline supports consistent communication among healthcare professionals, helps identify appropriate interventions, and enables researchers to evaluate change by comparing pre-treatment scores with outcomes after care. Its usefulness depends on clearly defined scoring procedures, reliable administration, and interpretation within the patient’s broader clinical context.

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Research

JoVE Journal - Medicine

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Receptor tyrosine kinases are ectopically expressed in many cancers and have been identified as therapeutic targets in acute leukemia. This manuscript describes an efficient strategy for pre-clinical evaluation of tyrosine kinase inhibitors for the treatment of acute leukemia.

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JoVE Journal - Immunology and Infection
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JoVE Journal - Environment
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Constructed wetland treatment systems have been used for decades to treat wastewater, but their application to treat oil sands process-affected waters is relatively new. To explore this potential, a surface flow mesocosm design and experimental methods are outlined. This approach aims to enhance our understanding of key design parameters and improve treatment efficacy.

Education

JoVE Core - Chemistry

pH Scale

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2020

Hydronium and hydroxide ions are present both in pure water and in all aqueous solutions, and their concentrations are inversely proportional as determined by the ion product of water (Kw). The concentrations of these ions in a solution are often critical determinants of the solution’s properties and the chemical behaviors of its other solutes. Two different solutions can differ in their hydronium or hydroxide ion concentrations by a million, billion, or even trillion times. A common means of...

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

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Here we outline the procedure for MRI-guided repetitive transcranial magnetic stimulation to the dorsomedial prefrontal cortex as an experimental treatment for major depressive disorder.

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