Rat Caudal Vertebrae

Rat caudal vertebrae are the series of small bones that form the rat’s tail, providing a defined model of segmental spinal anatomy and biomechanics. Each vertebra connects with neighboring segments through articulations, intervertebral tissues, ligaments, and surrounding muscles, allowing flexion and extension while transmitting mechanical loads along the tail. In medicine and biomedical research, these accessible vertebrae support studies of bone structure, joint mechanics, tissue injury, pain, and repair. Their repeated anatomy can also aid imaging, dissection, and evaluation of musculoskeletal interventions, linking basic vertebral biology with broader questions in spinal health and regenerative medicine.

Rat Caudal Vertebrae - Related Videos

Education

JoVE Core - Anatomy and Physiology

General Structure of a Vertebra

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2025

A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous column.

Research

JoVE EoE - Bacterial Pathogenesis and Host Interactions

Microinjection of Bacteria into the Caudal Vein of Zebrafish Embryos

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2026

Source: Shi, J., et al., Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens. J. Vis. Exp. (2020)This video demonstrates the procedure for preparing an Agrobacterium tumefaciens culture by inducing virulence gene expression with acetosyringone, followed by antibiotic removal through washing and resuspension, to generate a transformation-ready suspension for gene delivery into plant tissues.

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

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2025

Here, we present a method for assessing the activation and block of sensory axons in peripheral nerves in acute, anesthetized, in vivo rat experiments using two types of spinal electrophysiological measurements that can discriminate the activity of nerve fiber subtypes: Local Field Potentials and Wide Dynamic Range single neuron recordings.

Intrathecal Delivery of a Test Compound to the Rat Central Nervous System

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2025

Source: Chen, Y., et al. Intrathecal Delivery of Antisense Oligonucleotides in the Rat Central Nervous System. J. Vis. Exp. (2019)This video demonstrates the delivery of a test compound into the cerebrospinal fluid (CSF) through a catheter implanted in the lumbar spinal column of a rat model. The compound circulates along the CSF to the brain and spinal cord, enters neurons, and offers therapeutic potential.

Performing Thoracic Spinal Cord Hemisection Surgery in Rats

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2025

This video demonstrates the surgical procedure for performing a thoracic spinal cord hemisection in rats. It outlines the steps to expose the T8 spinal cord segment, perform the hemisection to disrupt neural tracts on one side, and provide post-operative care.

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