Vacuum-assisted Biopsy
Vacuum-assisted Biopsy - Related Videos
02:44
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Source: Schregel, K., et al. Optimized Management of Endovascular Treatment for Acute Ischemic Stroke. J. Vis. Exp. (2018).This video demonstrates the endovascular treatment of acute ischemic stroke using the stent retriever-assisted vacuum-locked extraction technique. A guiding sheath is introduced through the femoral artery to reach the clot. A catheter with a stent retriever secures and extracts the clot. Vascular imaging is done to confirm successful reperfusion.
06:20
Proper Operation of Vacuum Based Equipment
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2023
Source: Robert M. Rioux, Ajay Sathe & Zhifeng Chen, Pennsylvania State University, University Park, PA Vacuum is required for a number of laboratory procedures. This is most routinely achieved in the laboratory by the use of vacuum pumps. In addition to working at low pressures, vacuum pumps can also be used to enable rapid changing of the atmospheres in a reactor or flask by evacuation and backfilling.
09:41
Magnet Assisted Composite Manufacturing: A Flexible New Technique for Achieving High Consolidation Pressure in Vacuum Bag/Lay-Up Processes
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A new technique for applying consolidation pressure on the vacuum bag lay-up to fabricate composite laminates is described. The goal of this protocol is to develop a simple, cost-effective technique to improve the quality of laminates fabricated by the wet lay-up vacuum bag method.
09:19
Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
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Cited by 2 •
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This protocol describes the extraction of volatile organic compounds from a biological sample with the vacuum-assisted sorbent extraction method, gas chromatography coupled with mass spectrometry using the Entech Sample Preparation Rail, and data analysis. It also describes culture of biological samples and stable isotope probing.
05:26
A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications
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Cited by 3 •
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The liquid biopsy has revolutionized our approach to oncology translational studies, with sample collection, quality, and storage being crucial steps for its successful clinical application. Here we describe a standardized and validated protocol for downstream circulating-free DNA applications that can be applied in most translational research laboratories.
FAQs
The probe’s suction and cutter work as a coordinated sampling system. Vacuum pulls tissue into the probe aperture, while a rotating cutter separates a specimen without requiring a new skin entry for each sample. This arrangement allows multiple tissue pieces to be collected efficiently through one image-guided access point, supporting examination of lesion structure by pathology.
Image guidance links the suspected abnormality seen on mammography, ultrasound, or magnetic resonance imaging to the probe position. That alignment is important when a lesion is small or difficult to reach, because sampling must be directed at the intended target. More precise targeting can improve the usefulness of collected tissue for diagnostic assessment.
Compared with a surgical approach, this technique limits the extent of intervention by obtaining tissue through a single probe access point. The reduced intervention can lessen scarring, while the suction-assisted cutter can sometimes remove a benign finding during sampling. It therefore serves diagnostic needs and, in selected cases, limited removal of noncancerous abnormalities.
During the procedure, imaging first identifies and guides access to the suspicious lesion. The probe is then positioned so the target enters its aperture; suction draws tissue inward, and the rotating cutter removes specimens. Multiple samples can be obtained without repeatedly inserting separate instruments. The collected material is sent for pathological examination, which supplies the diagnostic tissue assessment.
In medicine, the method is used widely for breast abnormalities identified on mammography, ultrasound, or magnetic resonance imaging. It is particularly useful when a small lesion or a difficult-to-reach target requires multiple specimens. Its ability to gather tissue through one probe can support fuller pathological evaluation while avoiding more extensive surgical sampling.
Pathological examination of the specimens can help establish a tissue-based diagnosis and guide subsequent treatment planning. The procedure therefore connects image-based detection with direct laboratory assessment of the lesion. Efficient sampling, precision, and reduced scarring may help clinicians obtain clinically useful information while limiting the need for more extensive surgical intervention.