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JoVE Journal
Neuroscience

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Systemic and Local Drug Delivery for Treating Diseases of the Central Nervous System in Rodent Models
 

Systemic and Local Drug Delivery for Treating Diseases of the Central Nervous System in Rodent Models

Article doi: 10.3791/1992
August 16th, 2010 Usage Statistics

Summary August 16th, 2010

Thorough preclinical testing of drugs that act in the central nervous system often involves assessing and comparing drug biodistribution in association with specific routes of administration. Here, three commonly used methods of systemic delivery (intravenous, intraperitoneal, and oral) as well as a method for local delivery (convection-enhanced delivery) are demonstrated in mice.

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