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Biology
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Immunofluorescent Detection of Two Thymidine Analogues (CldU and IdU) in Primary Tissue
 

Immunofluorescent Detection of Two Thymidine Analogues (CldU and IdU) in Primary Tissue

Article doi: 10.3791/2166
December 7th, 2010 Usage Statistics

Summary December 7th, 2010

We have derived a strategy to detect sequential incorporation of thymidine analogues (CldU and IdU) into tissues of adult mice to quantify two successive rounds of cell division. This strategy is useful to detect cell turnover of long-lived tissues, oncogenic transformation, or transit-amplifying cells.

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