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Biology

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Live Imaging of Cell Extrusion from the Epidermis of Developing Zebrafish
 

Live Imaging of Cell Extrusion from the Epidermis of Developing Zebrafish

Article DOI: 10.3791/2689
June 27th, 2011

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Summary June 27th, 2011

Dying cells are extruded from epithelial tissues by concerted contraction of neighboring cells without disrupting barrier function. The optical clarity of developing zebrafish provides an excellent system to visualize extrusion in living epithelia. Here we describe methods to induce and image extrusion in the larval zebrafish epidermis at cellular resolution.

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