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Quantification of Orofacial Phenotypes in Xenopus
JoVE Journal
Biology
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JoVE Journal Biology
Quantification of Orofacial Phenotypes in Xenopus
DOI:

09:26 min

November 06, 2014

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Chapters

  • 00:05Title
  • 01:04Preparing the Head Mounting Dish
  • 01:58Photographing the Orofacial Region
  • 03:34Analyzing the Facial Dimensions
  • 04:23Quantitative Analysis and Morphometrics
  • 07:55Results: Orofacial Morphology after Retenoic Acid Receptor Inhibitor Treatment
  • 09:00Conclusion

Summary

Automatic Translation

A method to quantify the orofacial size and shape of Xenopus laevis embryos has been developed. In this protocol, traditional size measurements are combined with geometric morphometrics to allow for more sophisticated analyses of orofacial development and defects.

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