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Facial Transplants in Xenopus laevis Embryos
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Facial Transplants in Xenopus laevis Embryos

Article DOI: 10.3791/50697 • 09:08 min • March 26th, 2014
March 26th, 2014 •
*1,3, *4, 2,3
1Biological Sciences in Dental Medicine, Harvard University, 2Biology Department, Massachusetts Institute of Technology, 3Whitehead Institute, Massachusetts Institute of Technology, 4Biology Department, Virginia Commonwealth University
* These authors contributed equally

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Summary
Automatic Translation

A technique for transplanting "Extreme Anterior Domain" facial tissue between Xenopus laevis embryos has been developed. Tissue can be moved from one gene expression background into another, allowing the study of local requirements for craniofacial development and for signaling interactions between facial regions.

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Facial Transplants Xenopus Laevis Embryos Craniofacial Birth Defects Signaling Pathways Tissue Patterning Face Transplant Technique Extreme Anterior Domain (EAD) Chimeric Face Gene Function Lineage Label Healing Process Signaling Pathway Roles Xenopus As A Model Face Development Micromanipulation Embryonic Development
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