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JoVE Journal
Bioengineering

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A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
 

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Article doi: 10.3791/53588
May 9th, 2016

Summary May 9th, 2016

Soft-lithography was utilized to produce a representative true-scale model of pulmonary alveolated airways that expand and contract periodically, mimicking physiological breathing motion. This platform recreates respiratory acinar flows on a chip, and is anticipated to facilitate experimental investigation of inhaled aerosol dynamics and deposition in the pulmonary acinus.

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