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Cancer Research

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Drug Screening of Primary Patient Derived Tumor Xenografts in Zebrafish
 

Drug Screening of Primary Patient Derived Tumor Xenografts in Zebrafish

Article doi: 10.3791/60996
April 10th, 2020

Summary April 10th, 2020

Zebrafish xenograft models allow for high-throughput drug screening and fluorescent imaging of human cancer cells in an in vivo microenvironment. We developed a workflow for large scale, automated drug screening on patient-derived leukemia samples in zebrafish using an automated fluorescence microscope equipped imaging unit.

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