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JoVE Journal
Bioengineering

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Mitigation of Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilization
 

Mitigation of Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilization

Article doi: 10.3791/61545
December 3rd, 2020

Summary December 3rd, 2020

Presented here is a protocol for appending peptide CD47 (pepCD47) to metal stents using polybisphosphonate chemistry. Functionalization of metal stents using pepCD47 prevents the attachment and activation of inflammatory cells thus improving their biocompatibility.

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