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Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo
Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins <em>In Vitro</em> and <em>In Vivo</em>
JoVE Journal
Biochemistry
This content is Free Access.
JoVE Journal Biochemistry
Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo

Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo

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07:19 min

August 04, 2021

DOI:

07:19 min
August 04, 2021

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Summary

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Bioluminescence-light emitted by a luciferase enzyme oxidizing a small-molecule substrate, a luciferin-can be harnessed to activate photosensory proteins, thereby adding another dimension to light stimulation and enabling the manipulation of a multitude of light-mediated functions in cells across temporal and spatial scales.

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