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JoVE Journal Neuroscience
An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice
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An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice

Article DOI: 10.3791/64863-v • 08:59 min • March 3rd, 2023
March 3rd, 2023 •
1,2, 1, 1, 1, 1, 1,2, 1,2
1Division of Systems Neuroscience, New York State Psychiatric Institute, 2Department of Psychiatry, Columbia University

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Summary
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Here, we present a simplified open-source hardware and software setup for investigating mouse spatial learning using virtual reality (VR). This system displays a virtual linear track to a head-restrained mouse running on a wheel by utilizing a network of microcontrollers and a single-board computer running an easy-to-use Python graphical software package.

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Spatial Learning Head-restrained Mice Researchers Stimuli Modular Electronic Setup Inexpensive Easy To Set Up Compact Multiple Behavioral Setups Training Integration Visual Virtual Reality Environments Species And Preparations Human Psychophysics Neuroimaging Procedure Carla Diaz Hannah Chung Research Assistants Rotary Encoder Component Rotary ESP32 Wires Connection Behavior ESP32 Serial RX/TX Wires
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