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A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice
JoVE Journal
Behavior
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JoVE Journal Behavior
A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice

A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice

DOI:
10.3791/56988-v

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05:49 min

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July 21, 2018

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, ,
1UCL Sainsbury Wellcome Centre for Neural Circuits and Behaviour, 2MRC Laboratory of Molecular Biology

Chapters

  • 00:05Title
  • 00:34Behavioral Apparatus Setup
  • 02:10Visual & Auditory Stimulus Setup
  • 02:43Standard Behavioral Assay
  • 04:27Results: Mice Escape Responses Are Fast Goal-Directed Behaviors in Which Visual Cues Are not Used as Guidance
  • 05:07Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol describes a behavioral assay, based on the Barnes maze test, to study how instinctive defensive actions are modified by the knowledge of spatial environment.

Tags

Keywords: Spatial MemoryInstinctive DefenseBehavioral AssayGoal-directed NavigationVisual CuesShelterLEDUltrasound SpeakerAversive Auditory StimuliAversive Visual StimuliInfrared LightsInfrared CameraSoftware TrackingMouse BehaviorOlfactory Cues

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