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Author Spotlight: Advancements in Multichannel Extracellular Recording for Studying Neuronal Activity in Freely Moving Mice
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Multichannel Extracellular Recording in Freely Moving Mice

Author Spotlight: Advancements in Multichannel Extracellular Recording for Studying Neuronal Activity in Freely Moving Mice

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01:44 min

May 26, 2023

DOI:

01:44 min
May 26, 2023

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We aim to uncover the properties of neuronal firing and network local field potentials in behaving mice carrying out specific tasks by correlating the electrophysiological signal with behaviors. Multichannel extracellular recording by the micro-drive system has been shown to be a suitable and a efficient technology for neural activity during behavioral tests. Multichannel recording in free-moving mice has been deemed to be a useful technology in neuroscience studies, but it’s still quite challenging for beginners to acquire and analyze the signals.

We introduced how to perform the multichannel extracellular recording in freely-moving mice with a more steady and lightweight micro-drive system, and optimize the processes of recording and data analysis for the beginners. We are going to increase the number of channels and reduce the volume of micro-driver system in a new version.

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