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Journal
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Biochemistry
/
Identifying G-Quadruplexes in a DNA Template Using Chemical Mapping
/
Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping (Video) | JoVE
JoVE Journal
Biochemistry
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JoVE Journal
Biochemistry
In Vitro
Chemical Mapping of G-Quadruplex DNA Structures by
Bis
-3-Chloropiperidines
Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping (Video) | JoVE
Identifying G-Quadruplexes in a DNA Template Using Chemical Mapping
DOI:
10.3791/65373-v
•
01:53 min
•
May 12, 2023
•
Alice Sosic
,
Cristina Dal Lago
,
Richard Göttlich
,
Barbara Gatto
1
Department of Pharmaceutical and Pharmacological Sciences
,
University of Padova
,
2
Institute of Organic Chemistry
,
Justus Liebig University Giessen
Tags
Keywords: G-quadruplex
DNA
Chemical Mapping
Bis-3-chloropiperidines
B-CePs
TBA
Thrombin-binding Aptamer
DNA Secondary Structure
In Vitro Characterization
Nucleic Acid Analysis
Alkylation
DNA Cleavage
PAGE
Biologically Relevant
Therapeutic Targets
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