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JoVE Journal
Chemistry
Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Fram...
Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Fram...
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods

Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods

Full Text
4,447 Views
07:20 min
October 6, 2023

DOI: 10.3791/65441-v

Marvin Radke1, Ralf Suren1, Norbert Stock1

1Department of Inorganic Chemistry,Kiel University

The targeted synthesis of new metal-organic frameworks (MOFs) is difficult, and their discovery depends on the knowledge and creativity of the chemist. High-throughput methods allow complex synthetic parameter fields to be explored quickly and efficiently, accelerating the process of finding crystalline compounds and identifying synthetic and structural trends.

I see the periodic table as a huge playground, and in our research, we focus on the synthesis of new materials, porous materials, such as this here, that's a structural model, and we see holes in the framework, and that can be used to store molecules or also to separate molecules based off on the size of these. And in addition to that kind of studies, we also develop new reactor systems in order to accelerate the discovery process. The current experimental challenges are to further accelerate the synthesis and characterization process with additional high throughput instrumentation, such as high throughput absorption characterization device.

The leg of detail and publications regarding the synthesis and characterization procedure affecting reproducibility is a well known problem in chemistry. By providing a thorough description of our method and setup, we aim to encourage other groups to adopt the described methodology, thereby increasing the reproducibility of experimental studies. We do not know what the future will bring, since we work on the discovery of new materials, and we never know what kind of properties these materials will have.

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