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A Necrotizing Enterocolitis Model for Mechanistic Studies and Drug Discovery

Article DOI: 10.3791/65605-v • 00:57 min • July 28th, 2023
July 28th, 2023 •
1, 1, 1, 2, 3, 1, 1, 1, 1
1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of North Carolina at Chapel Hill, 2University of Nebraska College of Medicine, 3Department of Surgery, Washington University School of Medicine

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Mikrofluidisches Modell nekrotisierende Enterokolitis humane neonatale Darmenteroide dysbiotisches Mikrobiom komplexe Pathogenese intestinale Tight Junctions Durchlässigkeit der Darmbarriere Epithelzelltod mikrobielle Dysbiose dysregulierte Entzündung Tiermodelle Zelllinien Darmorganoide In-vitro-Modell Mikrofluidik-Technologie NEC-on-a-Chip Frühgeborenes menschliche Endothelzellen Arzneimittelforschungstests
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