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A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
JoVE Journal
Medicine
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JoVE Journal Medicine
A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
DOI:

07:24 min

December 28, 2016

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Chapters

  • 00:05Title
  • 01:22Preparation for Testing
  • 02:15Lot Verification Procedure
  • 03:05Blood Sample Collection
  • 04:14Testing Procedure
  • 05:06Results: Lateral Flow Immunoassay Ensures Precise Hemoglobin S Measurements
  • 05:48Conclusion

Summary

Automatic Translation

We have developed a point-of-care immunoassay to rapidly quantify hemoglobin S (HbS) levels during transfusion therapy for sickle cell disease (SCD) patients. By applying a small amount of treated blood to the device, the healthcare provider can determine the %HbS in a SCD patient to immediately inform clinical decisions.

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