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Morphological and Functional Evaluation of Axons and their Synapses during Axon Death in Drosophila melanogaster

Article DOI: 10.3791/60865-v • 10:29 min • March 16th, 2020
March 16th, 2020 •
*1, *1, 1, 1
1Department of Fundamental Neurosciences, University of Lausanne
* These authors contributed equally

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Summary
Automatic Translation

Here, we provide protocols to perform three simple injury-induced axon degeneration (axon death) assays in Drosophila melanogaster to evaluate the morphological and functional preservation of severed axons and their synapses.

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Morphological Evaluation Functional Evaluation Axon Death Drosophila Melanogaster Injury Protocol Preservation Of Axonal Morphology Synaptic Morphology Synaptic Function Axonal Transport Axonal Organelles Wing Injury Assay Degeneration Of Axons Nerve Bundle Optogenetics Antennal Ablation Neuronal Maintenance Factors Wild-type Flies Optogenetics Setup
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