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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

Article DOI: 10.3791/3680-v • 13:10 min • April 4th, 2012
April 4th, 2012 •
1, 2, 1, 2, 1, 3, 1, 4, 2
1Carestream Molecular Imaging, 2Department of Chemistry and Biochemistry, University of Notre Dame, 3Freimann Life Science Center, University of Notre Dame, 4Research and Development, Oncovision, GEM-Imaging S.A.

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Fat content analysis is routinely conducted in studies utilizing murine obesity models. Emerging methods in small animal CT imaging and analysis are providing for longitudinal detail rich fat content analysis. Here we detail step by step procedures for performing small animal CT imaging, analysis, and visualization.

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Segmentation Measurement Fat Volumes Murine Obesity Models X-ray Computed Tomography Environmental Factors Genetic Factors Disease Mechanisms Small Animal Models Of Obesity Fat Content Data Invasive Methods Non-invasive Methods Dual Energy X-ray Absorptiometry (DEXA) Magnetic Resonance (MR) Organ-specific Fat Distribution Region-specific Fat Distribution Longitudinal Assessments Small Animal CT Systems
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