Surgical Evaluation
Surgical Evaluation - Related Videos
07:32
Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
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Cited by 22 •
2020
The current protocol establishes a rigorous and reproducible method for quantification of morphological joint changes that accompany osteoarthritis. Application of this protocol can be valuable in monitoring disease progression and evaluating therapeutic interventions in osteoarthritis.
13:37
A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
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Cited by 33 •
2014
A mouse tumor model of surgical stress is used to explore how postoperative immune suppression promotes metastatic disease and to evaluate immunostimulatory perioperative therapies.
03:59
Surgical Correction for Pediatric Epiblepharon and Trichiasis
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2025
Here, we present a protocol for surgical correction for pediatric epiblepharon and trichiasis.
04:54
A Rat Surgical Skin Wound Model: An Approach for Wound Healing Studies and Biomaterial Evaluation
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2026
A rat skin wound model that enables the evaluation of various therapeutic agents under physiological or pathological conditions across the distinct stages of the healing process is described. Furthermore, a protocol for performing manual planimetry to monitor the wound contraction rate throughout tissue repair is detailed.
08:45
Evaluation of 3D Spheroids for AAV Transduction Studies
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2026
Three-dimensional spheroid culture systems improve upon conventional 2D models for AAV gene therapy development. This methodology enables sensitive detection of AAV transduction at low doses, enhanced physiological relevance, and robust long-term monitoring. The platform supports potency assessment, high-throughput screening, and vector optimization across diverse cell lines and AAV serotypes.
FAQs
Suitability depends on how the patient’s overall health interacts with the proposed operation. Clinicians integrate the history, examination, imaging, laboratory results, medication profile, and identified risks rather than relying on one finding. This integrated view clarifies whether expected benefit justifies concerns such as bleeding, infection, anesthesia complications, or delayed recovery, and supports a safer operative plan.
Medication review is important because a patient’s current treatment forms part of the perioperative risk assessment. Examining the medication profile alongside the medical history and test results helps clinicians identify issues relevant to preparation and monitoring. These findings can influence planning before the operation and help the team anticipate factors that could complicate perioperative care or recovery.
Diagnostic testing contributes more than confirmation of a suspected condition. Imaging and laboratory tests add objective information to the history and physical examination, helping clinicians clarify the diagnosis and judge operative risk. Their results can support selection of an appropriate procedure, reveal a condition needing attention before surgery, and provide a basis for coordinated clinical decisions.
The process connects clinical findings to several decisions: whether surgery is appropriate, which procedure best fits the patient’s condition, and what preparation is required. Clinicians also use the assessment to explain expected benefits and risks during informed consent. Afterward, the same findings help determine what aspects of care require postoperative monitoring.
Results may affect whether surgery proceeds, which procedure is selected, and how the patient is prepared. They also inform the discussion of expected benefits and risks during informed consent. If the assessment identifies a condition requiring treatment first, clinicians can address it before operating rather than proceeding without appropriate preparation.
Different clinicians can contribute to interpreting the patient’s condition, operative suitability, and perioperative needs. This coordination helps connect diagnostic findings with procedure planning, informed consent, and postoperative monitoring. It is especially useful when the evaluation identifies issues that require treatment before surgery, because care can be organized before the operation.