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Mapping Cerebral Blood Flow and Electrical Fields: Electrode Placement in Mice

June 2nd, 2023
1, 1, 2, 1,3,4,5
1Department of Neurosurgery, Duke University Medical Center, 2Department of Anesthesiology and Pain Management, University Texas Southwestern Medical School, 3Department of Neurobiology, Duke University Medical Center, 4Department of Biomedical Engineering, Duke University, 5Research and Surgery Services, Durham VA Medical Center

Summary
Automatic Translation

Vi beskriver en protokoll for vurdering av dose-responskurver for ekstrakraniell stimulering med tanke på elektriske feltmålinger i hjernen og relevant biomarkør-cerebral blodstrøm. Siden denne protokollen innebærer invasiv elektrodeplassering i hjernen, er generell anestesi nødvendig, med spontan pust foretrukket i stedet for kontrollerte respirasjoner.

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