Journal
/
/
Les analyses toxicologiques pour Effets d'essais d'un médicament épigénétique sur le développement, la fécondité et de la survie du paludisme moustiques
JoVE 杂志
生物学
需要订阅 JoVE 才能查看此.  登录或开始免费试用。
JoVE 杂志 生物学
Toxicological Assays for Testing Effects of an Epigenetic Drug on Development, Fecundity and Survivorship of Malaria Mosquitoes
DOI:

10:26 min

January 16, 2015

, ,

Chapters

  • 00:05Title
  • 01:22Immature Mosquito Development and Survivorship Assays
  • 03:17Fecundity Assay by Administering Drug Through Artifitial Feeder to Female Mosquitoes
  • 05:56Biochemical Assay of Mosquito Enzyme Inhibition by Drug
  • 08:25Results: Effect of DZNep on Malaria Mosquitoes
  • 10:00Concluision

Summary

自动翻译

A protocol is developed to examine the effects of an epigenetic drug DZNep on the development, fecundity and survivorship of mosquitoes. Here we describe procedures for the aqueous exposure of DZNep to immature mosquitoes and a blood-based exposure of DZNep to adult mosquitoes in addition to measuring SAH hydrolase inhibition.

Related Videos

Read Article