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JoVE Journal Genetics
In vivo Forward genetisk Screen å identifisere Novel nervecellene gener i Drosophila melanogaster
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In vivo Forward genetisk Screen å identifisere Novel nervecellene gener i Drosophila melanogaster

Article DOI: 10.3791/59720-v • 10:00 min • July 11th, 2019
July 11th, 2019 •
1, 1, 1, 1, 1, 2, 2, 1, 2, 1
1Department of Biological Sciences, University of Alabama, 2Department of Genetics, University of Wisconsin-Madison

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Vi presenterer en protokoll ved hjelp av en frem genetisk tilnærming til skjermen for mutanter stiller neurodegeneration i Drosophila melanogaster. Det inkorporerer en klatring analysen, histologi analyse, gen kartlegging og DNA-sekvensering til slutt identifisere romanen gener knyttet til prosessen med neuroprotection.

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Genetikk Drosophila melanogaster neurodegeneration frem genetisk skjerm klatring analysen histologi gen kartlegging DNA sekvensering
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