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Journal / Cancer Research / 患者生物流体中肿瘤相关循环DNA的检测与监测…
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Cancer Research

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患者生物流体中肿瘤相关循环DNA的检测与监测

Article DOI: 10.3791/59721-v • 06:53 min • June 8th, 2019
June 8th, 2019 •
1,2, 1, 1,2, 3, 1, 4,5, 1,2,5
1Center for Genetic Medicine, Children's National Health System, 2Institute for Biomedical Sciences, The George Washington University School of Medicine and Health Sciences, 3Dana-Farber Cancer Institute, 4Department of Neurology, University of California San Francisco, 5DIPG Centre of Expertise Zurich, Universitats-Kinderspital Zurich

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在这里,我们提出一个协议,以检测肿瘤体突变在循环DNA存在于患者生物流体(生物流体)。我们的滴数字聚合酶链反应(dPCR)方法能够定量肿瘤突变等位基因频率(MAF),促进对肿瘤反应的诊断和时间监测的微创补充。

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癌症研究,第148期,液体活检,数字液滴PCR,循环细胞游出DNA,血浆,血清,脑脊液
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