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JoVE Journal Neuroscience
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Insights into the Techniques and Findings of Recent Advancements in Epilepsy Research (Video) | JoVE

Monitoring Epileptiform Events in Drosophila via Calcium Imaging

Article DOI: 10.3791/65825-v • 01:35 min • October 13th, 2023
October 13th, 2023 •
1, 2, 2, 2, 3,4, 1
1Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, 2The Second Clinical Medicine School of Guangzhou Medical University, 3Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, The Third Affiliated Hospital of Guangzhou Medical University, 4Key Laboratory for Reproductive Medicine of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University

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Imaging del calcio ex vivo modello di Drosophila epilessia disturbo neurologico convulsioni ricorrenti origine genetica tecnologia di imaging indicatori di calcio geneticamente codificati GCaMP6 risoluzione a livello cerebrale risoluzione a singola cellula genetica molecolare saggi comportamentali protocollo drosofila adulta attività epilettiformi microscopio confocale attività neurale saggio comportamentale simile a convulsioni sensibile al bang mosche knockdown del gene Cac attività anomale del calcio screening genetico patogeno
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