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JoVE Journal Neuroscience
Simultaneous Electrophysiological Recording and Micro-injections of Inhibitory Agents in the Rodent Brain
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Simultaneous Electrophysiological Recording and Micro-injections of Inhibitory Agents in the Rodent Brain

Article DOI: 10.3791/52271-v • 07:52 min • July 7th, 2015
July 7th, 2015 •
1, 1, 1, 1
1École d'optométrie, Université de Montréal

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Summary
Automatic Translation

Here, we craft a glass pipette with dual functions: inhibition of deep brain structures by microinjections of drugs and real-time monitoring of their effects through simultaneous electrophysiological recordings.

Tags

Simultaneous Electrophysiological Recording Micro-injections Inhibitory Agents Rodent Brain Injectrode Construction Probing System Drug Delivery Glass Pipette Modification Hypodermic Needle Silver Filament Microsyringe Pump Real-time Pharmacodynamics Feedback Multi-unit Extracellular Signals Superior Colliculus Neuronal Activity Flashes Of Light Drug Localization Control Chemical Substance Choice Anatomic Experiments
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