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Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure
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Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

Article DOI: 10.3791/55895-v • 07:29 min • August 14th, 2017
August 14th, 2017 •
1,2,3, 2, 3, 1,4, 1,4
1Institute of Physiology - Center for Integrative Human Physiology, University of Zurich, 2Department of Surgery, Rush University Medical Center, 3Department of Surgery, Cantonal Hospital Winterthur, 4Institute of Anesthesiology, University and University Hospital Zurich

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Inducing rapid liver hypertrophy using Associating Liver Partition and Portal vein ligation for a Staged hepatectomy (ALPPS) has been proposed for resection of borderline resectable liver tumors. This model may elucidate mechanisms involved in rapid hypertrophy and allows testing of drugs that promote or block the acceleration of regeneration.

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Rat Model Associating Liver Partition And Portal Vein Ligation For Staged Hepatectomy ALPPS Procedure Hypertrophy Portal Vein Ligation Transection Of Parenchyma Physiological Assessment Molecular Assessment Liver Regeneration Accelerated Liver Regeneration Human Surgery Borderline Resectable Liver Tumors Anesthesia Surgery Preparation Abdominal Incision Abdominal Wall Silk Stay Sutures Small Wire Retractors Hepatoduodenal Ligament Portal Vein Branches
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