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Immunology and Infection

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JoVE Journal Immunology and Infection
Un approccio semplice ed efficiente per costruire Mutant vaccinia vettori di virus
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Un approccio semplice ed efficiente per costruire Mutant vaccinia vettori di virus

Article DOI: 10.3791/54171-v • 09:16 min • October 30th, 2016
October 30th, 2016 •
*1, *2,3, 1, 1,2,3, 1,2,3
1Center for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, 2Sino-British Research Centre for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, Zhengzhou University, 3School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University
* These authors contributed equally

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virus vaccinico (VV) è stato ampiamente utilizzato nella ricerca biomedica e il miglioramento della salute umana. Questo articolo descrive un metodo semplice e altamente efficiente per modificare il genoma VV utilizzando un sistema CRISPR-Cas9.

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L'infezione virus vaccinico genoma la modifica la ricombinazione omologa CRISPR Cas9
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